IDENTIFICATION OF NUMERICAL CHANGES IN CELL DNA

摘要

The present invention relates to a process for identifying numerical changes in cell DNA, comprising the following steps: (a) isolating DNA from normal cells and amplifying the DNA by means of a PCR method using tag primers; (b) hybridizing cells under study in situ with the amplified DNA from (a); (c) amplifying DNA from the in situ hybridized cells from (b) by means of a PCR method using the tag primers from (a), and (d) identifying numerical changes in the amplified DNA from (c) in a normal way. In addition, the invention concerns a kit suitable for carrying out the process.