发明名称 |
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds |
摘要 |
Disclosed are compounds which inhibit beta-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits beta-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
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申请公布号 |
US2002137738(A1) |
申请公布日期 |
2002.09.26 |
申请号 |
US20010915564 |
申请日期 |
2001.07.27 |
申请人 |
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发明人 |
WU JING;TUNG JAY S.;THORSETT EUGENE D.;PLEISS MICHAEL A.;NISSEN JEFFREY S.;NEITZ JEFFREY;LATIMER LEE H.;JOHN VARGHESE;FREEDMAN STEPHEN;BRITTON THOMAS C.;AUDIA JAMES E.;REEL JON K.;MABRY THOMAS E.;DRESSMAN BRUCE A.;CWI CYNTHIA L.;DROSTE JAMES J.;HENRY STEVEN S.;MCDANIEL STACEY L.;SCOTT WILLIAM LEONARD;STUCKY RUSSELL D.;PORTER WARREN J. |
分类号 |
A61K31/40;A61K31/4015;A61K31/445;A61K31/55;A61K38/04;A61K38/05;A61P25/28;C07D223/18;C07D471/04;C07D471/06;C07D471/08;(IPC1-7):A61K31/55;A61K31/401;A61K31/13 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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