发明名称 N-(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
摘要 Disclosed are compounds which inhibit beta-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed pharmaceutical compositions comprising a compound which inhibits beta-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
申请公布号 US2002137743(A1) 申请公布日期 2002.09.26
申请号 US20010984834 申请日期 2001.10.31
申请人 WU JING;THORSETT EUGENE D.;NISSEN JEFFREY S.;MABRY THOMAS E.;LATIMER LEE H.;JOHN VARGHESE;FANG LAWRENCE Y.;AUDIA JAMES E. 发明人 WU JING;THORSETT EUGENE D.;NISSEN JEFFREY S.;MABRY THOMAS E.;LATIMER LEE H.;JOHN VARGHESE;FANG LAWRENCE Y.;AUDIA JAMES E.
分类号 A61K31/198;A61K31/223;A61K31/277;(IPC1-7):A61K31/54;A61K31/535;A61K31/495;A61K31/44 主分类号 A61K31/198
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