发明名称 |
Antisense oligonucleotide inhibition of specific histone deacetylase isoforms |
摘要 |
This invention relates to the inhibition of histone deacetylase expression and enzymatic activity. The invention provides methods and reagents for inhibiting specific histone deacetylase (HDAC) isoforms by inhibiting expression at the nucleic acid level or enzymatic activity at the protein level.
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申请公布号 |
US2002137162(A1) |
申请公布日期 |
2002.09.26 |
申请号 |
US20010817538 |
申请日期 |
2001.03.26 |
申请人 |
LI ZUOMEI;BONFILS CLAIRE;BESTERMAN JEFFREY M. |
发明人 |
LI ZUOMEI;BONFILS CLAIRE;BESTERMAN JEFFREY M. |
分类号 |
A61K31/167;A61K31/18;A61K31/4035;A61K31/4418;A61K31/711;(IPC1-7):C12N9/99;C07H21/04;C12P21/02 |
主分类号 |
A61K31/167 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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