| 摘要 |
<p>The present invention relates to all facets of novel polynucleotides, including the polypeptides they encode, and antibodies and specific-binding partners thereto, and their applications to research, diagnosis, prognosis, drug discovery, therapy, clinical medicine, forensic science, etc. The polynucleotides are differently expressed in T-cells and are therefore are useful in variety of ways, including but not limited to, as molecular markers, as drug targets, and for detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, determining predisposition to, etc., diseases and conditions, especially relating to the immune system. The identification of specific genes, and groups of genes, expressed in a pathway physiologically relevant to T-cell differentiation and function permits the delineation of signaling and disease pathways, and the definition of targets in these pathways which are useful in diagnostic therapeutic, and clinical applications.</p> |
