摘要 |
<p>A process for the preparation of 2-hydroxymethyl-pyrrolidine-3,4-diols of the formulae comprising the steps of a) biooxidation of N-protected aminotetraols of the formula b) deprotection of the corresponding N-protected 5-amino-5-deoxy-pentulose c) hydrogenation of the corresponding 5-amino-5-deoxy-pentulose.</p> |