| 发明名称 |
METHODS AND COMPOSITIONS UTILIZING 2'-5' OLIGOADENYLATES IN THE TREATMENT OF DISORDERS OF CELL PROLIFERATION |
| 摘要 |
2'5'-oligoadenylate-2'3'-cyclophosphates having the chemical strucutre of Formula (I) wherein 0 </=n</=10, or the pharmaceutically acceptable salts thereof, inhibit cell proliferation and tumor cell growth, and are therefore useful in methods and compositions for the treatment of disorders of cell proliferation, including cancer, and also in the reduction of tumor size.
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| 申请公布号 |
WO02060455(A8) |
申请公布日期 |
2002.09.26 |
| 申请号 |
WO2001US50386 |
申请日期 |
2001.10.24 |
| 申请人 |
DANA-FARBER CANCER INSTITUTE, INC.;EDSON, CLARK;ACKERMAN, SAMUEL |
发明人 |
EDSON, CLARK;ACKERMAN, SAMUEL |
| 分类号 |
A61K31/70;A61K31/7125;A61P17/00;A61P17/06;A61P35/00;(IPC1-7):A61K31/712 |
主分类号 |
A61K31/70 |
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