| 发明名称 |
Hepatitis E virus vaccine and method |
| 摘要 |
Antigen and antibody vaccine composition effective in preventing hepatitis E virus (HEV) infection are disclosed. The antigen composition includes peptides corresponding to carboxyl terminal end regions of the second and third open reasing frames of the HEV genome. The composition is effective in preventing HEV infection after vaccination. The antibody composition contains an antibody effective to block HEV infection of human primary hepatocytes in culture.
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| 申请公布号 |
US6455492(B1) |
申请公布日期 |
2002.09.24 |
| 申请号 |
US19920870985 |
申请日期 |
1992.04.20 |
| 申请人 |
GENELABS TECHNOLOGIES, INC. |
发明人 |
REYES GREGORY R.;BRADLEY DANIEL W.;TWU JR-SHIN;PURDY MICHAEL A.;TAM ALBERT W.;KRAWCZYNSKI KRZYSZTOF Z.;YARBOUGH PATRICE O. |
| 分类号 |
C12N15/09;A61K38/00;A61K39/00;A61K39/29;A61K39/395;A61P31/12;C07K14/08;C07K16/10;C12N15/51;C12P21/08;C12Q1/70;G01N33/576;(IPC1-7):A01N37/18;C07K16/00 |
主分类号 |
C12N15/09 |
| 代理机构 |
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