发明名称 |
Fremgangsmåde til fremstilling af formbart, dehydreret væv til implantation |
摘要 |
A process for preparing pliable soft tissue specimen which are resistant to cracking and devoid of viable cells includes the steps of treating native soft tissue obtained from a donor by a gradually increasing gradient of aliphatic alcohol or other suitable water miscible polar organic solvent until the last alcohol (or other solvent) solution has at least 25% by volume of the organic liquid. Thereafter, the tissue specimen is treated with a solution containing glycerol or low molecular weight (<1000 D) polyethylene glycol, and polyethylene glycol of a molecular weight between approximately 6,000 to 15,000 D and heparin. Thereafter, the tissue specimen is briefly immersed in aqueous heparin solution, frozen and lyophilized. The tissue specimen is suitable for implantation as a homograft or xenograft, with or without rehydration. |
申请公布号 |
DK1089776(T3) |
申请公布日期 |
2002.09.23 |
申请号 |
DK19990931880T |
申请日期 |
1999.06.23 |
申请人 |
INTERNATIONAL HEART INSTITUTE OF MONTANA FOUNDATION |
发明人 |
DURAN, CARLOS, M., G.;CHEUNG, DAVID, T.;PANG, DAVID, C. |
分类号 |
A61L27/36;(IPC1-7):A61L27/00 |
主分类号 |
A61L27/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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