| 发明名称 |
Heteroarylalkanoic acids as integrin receptor antagonists |
| 摘要 |
The present invention relates to a class of compounds represented by the Formula I or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively antagonizing the alphaVbeta3 and/or the alphaVbeta5 integrin without significantly antagonizing the IIb/IIIa or alphaVbeta6 integrin.
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| 申请公布号 |
US2002133023(A1) |
申请公布日期 |
2002.09.19 |
| 申请号 |
US20010881913 |
申请日期 |
2001.06.15 |
| 申请人 |
NAGARAJAN SRINIVASAN RAJ;KHANNA ISH KUMAR;TOLLEFSON MICHAEL B.;MOHLER SCOTT B.;CHEN BARBARA;RUSSELL MARK;DEVADAS BALEKUDRU;PENNING THOMAS D.;SCHRETZMAN LORI A.;SPANGLER DALE P.;BOYS MARK LAURENCE;CHANDRAKUMAR NIZAL SAMUEL;LU HUNG-FUN |
发明人 |
NAGARAJAN SRINIVASAN RAJ;KHANNA ISH KUMAR;TOLLEFSON MICHAEL B.;MOHLER SCOTT B.;CHEN BARBARA;RUSSELL MARK;DEVADAS BALEKUDRU;PENNING THOMAS D.;SCHRETZMAN LORI A.;SPANGLER DALE P.;BOYS MARK LAURENCE;CHANDRAKUMAR NIZAL SAMUEL;LU HUNG-FUN |
| 分类号 |
A61K31/4245;A61K31/4375;A61K31/4439;A61K31/444;A61K31/4545;A61K31/4709;A61K31/496;A61K31/5383;A61P3/14;A61P9/00;A61P9/08;A61P9/10;A61P19/02;A61P19/10;A61P21/00;A61P27/02;A61P35/00;A61P43/00;C07D213/74;C07D231/38;C07D233/60;C07D233/88;C07D405/12;C07D413/06;C07D413/12;C07D413/14;C07D417/12;C07D471/04;C07D498/04;(IPC1-7):C07D263/34 |
主分类号 |
A61K31/4245 |
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