| 发明名称 |
NUCLEIC ACIDS ENCODING A REGULATOR OF A G PROTEIN SIGNALING, RGS18, AND USES THEREOF |
| 摘要 |
The present invention relates to nucleic acids that encode novel Regulator of G protein Signaling RGS18 polypeptides. RGS18 polypeptides are abundantly expressed in platelets and comprise a novel RGS domain (RGS18 domain). The present invention also relates to RGS18 polypeptides. The invention also relates to means for the detection of RGS18 nucleic acids and RGS18 polypeptides. The invention also relates to methods for the detection of activators or inhibitors of RGS18 polypeptides. Finally, the present invention relates to methods of prevention and/or treatment of disorders or conditions associated with platelet activation dysfunction. |
| 申请公布号 |
WO0183514(A3) |
申请公布日期 |
2002.09.19 |
| 申请号 |
WO2001US13540 |
申请日期 |
2001.04.26 |
| 申请人 |
AVENTIS PHARMACEUTICALS INC.;MURRAY, DAVID, L.;GAGNON, ALISON, W. |
发明人 |
MURRAY, DAVID, L.;GAGNON, ALISON, W. |
| 分类号 |
G01N33/50;A61K31/7088;A61K35/76;A61K38/00;A61K48/00;A61L27/00;A61P7/02;A61P7/04;A61P9/00;A61P9/10;C07K14/47;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N7/00;C12N15/09;C12Q1/68;G01N33/15;G01N33/53;G01N33/566 |
主分类号 |
G01N33/50 |
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