| 发明名称 |
Method for gene transfer using Bcl2 and compositions useful therein |
| 摘要 |
A method for liver-directed gene therapy is described. The method involves transfer of Bcl2 and a selected transgene to hepatocytes. Bcl2 protects those hepatocytes which express it from apoptosis and permits proliferation of hepatocytes containing the transgene.
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| 申请公布号 |
US2002131961(A1) |
申请公布日期 |
2002.09.19 |
| 申请号 |
US20020060762 |
申请日期 |
2002.01.30 |
| 申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
WILSON JAMES M.;CHEN SHU-JEN |
| 分类号 |
A61K38/00;A61K48/00;C07K14/47;C07K14/505;C07K14/705;C07K14/81;C12N15/12;C12N15/65;C12N15/864;C12N15/87;(IPC1-7):A61K48/00;A61K39/235;C12N15/861 |
主分类号 |
A61K38/00 |
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