| 发明名称 |
Method for the preparation of fluticasone and related 17beta-carbothioic esters using a novel carbothioic acid synthesis and novel purification methods |
| 摘要 |
This invention discloses a novel method for the conversion of carboxylic acids to carbothioic acids and application of the method to the preparation of androstane carbothiolates, such as fluticasone propionate, which avoids column chromatography. |
| 申请公布号 |
US2002133032(A1) |
申请公布日期 |
2002.09.19 |
| 申请号 |
US20000513399 |
申请日期 |
2000.02.25 |
| 申请人 |
BARKALOW JUFANG;CHAMBERLIN STEVEN A.;COOPER ARTHUR J.;HOSSAIN AZAD;HUFNAGEL JOHN J.;LANGRIDGE DENTON |
发明人 |
BARKALOW JUFANG;CHAMBERLIN STEVEN A.;COOPER ARTHUR J.;HOSSAIN AZAD;HUFNAGEL JOHN J.;LANGRIDGE DENTON |
| 分类号 |
C07B61/00;C07C327/02;C07C327/06;C07C327/14;C07J31/00;(IPC1-7):C07J9/00 |
主分类号 |
C07B61/00 |
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