摘要 |
<p>It is intended to provide a novel protein useful in screening an agonist/an antagonist. A human-origin protein or its salt; a DNA encoding this protein; a method of determining a ligand to the protein; a screening method/a screening kit for a compound capable of altering the binding properties of the ligand to the protein; compounds obtained by the screening method or salts thereof, etc. The above-described human-origin protein or the DNA encoding the same are usable in: (1) determining a ligand to the protein; (2) preventives and/or remedies for diseases in association with the hypofunction of the above protein; (3) screening a compound (an agonist, an antagonist or the like) capable of altering the binding properties of the protein of the invention to the ligand; etc.</p> |