发明名称 |
Human DNA Ligase IV |
摘要 |
A human DNA Ligase IV polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide via gene therapy for the treatment of disorders associated with a defect in DNA Ligase IV. Antagonists against such polypeptides and their use as a therapeutic to destroy unwanted cells are also disclosed. Diagnostic assays to detect mutant DNA Ligase IV genes are also disclosed.
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申请公布号 |
US2002132331(A1) |
申请公布日期 |
2002.09.19 |
申请号 |
US20020141132 |
申请日期 |
2002.05.09 |
申请人 |
HUMAN GENOME SCIENCES, INC. |
发明人 |
WEI YING-FEI;HASELTINE WILLIAM A. |
分类号 |
C12N9/00;(IPC1-7):C12N9/22;C12Q1/68;C07H21/04;C12P21/02;C12N5/06 |
主分类号 |
C12N9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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