OPTICALLY ACTIVE CHROMAN AND THIOCHROMAN DERIVATIVES

摘要

The present invention includes a compound having the following general formula (1): <CHEM> in which X represents an oxygen atom or a sulfur atom, m represents an integer of 2 to 14, and n represents an integer of 2 to 7, or hydrates or pharmaceutically acceptable salts thereof. The compound of general formula (1) is advantageous in pharmaceutical use because of its far superior anti-estrogenic activity over the corresponding racemic mixture.