发明名称 1-aza-2-alky-6-aryl-cycloalkanes
摘要 Compound of formula (I):wherein:n represents 0 or 1,R1 represents hydrogen, arylalkyl, alkyl, acyl, alkoxycarbonyl, arylalkoxycarbonyl or trifluoroacetyl,R2 represents alkyl,X represents oxygen, chlorine, OR3, SR4 or NOR5,R3 represents hydrogen , alkyl, acyl, alkoxycarbonyl or arylalkoxycarbonyl,R4 represents hydrogen, alkyl or aryl,R5 represents hydrogen or optionally substituted alkyl,<CUSTOM-CHARACTER FILE="US06451789-20020917-P00900.TIF" ALT="custom character" HE="20" WI="20" ID="CUSTOM-CHARACTER-00001"/> represents a single or double bond,Ar represents aryl or heteroaryl, its isomers and addition salts thereof with a pharmaceutically acceptable acid, and medicinal products containing the same which are useful as facilitators of memory and cognition and antalgic agents.
申请公布号 US6451789(B1) 申请公布日期 2002.09.17
申请号 US20010964085 申请日期 2001.09.26
申请人 LES LABORTOIRES SERVIER 发明人 RAULT SYLVAIN;RENAULT OLIVIER;GUILLON JEAN;DALLEMAGNE PATRICK;RENARD PIERRE;PFEIFFER BRUNO;LESTAGE PIERRE;LEBRUN MARIE-CéCILE
分类号 C07D223/00;A61K31/44;A61K31/4427;A61K31/4433;A61K31/445;A61K31/4465;A61K31/45;A61K31/451;A61K31/4523;A61K31/4535;A61K31/4545;A61K31/55;A61P25/04;A61P25/16;A61P25/28;A61P29/00;A61P43/00;C07B61/00;C07D211/38;C07D211/46;C07D211/54;C07D211/72;C07D211/74;C07D211/84;C07D211/86;C07D223/08;C07D401/04;C07D409/04;(IPC1-7):A61K31/55;C07D223/02 主分类号 C07D223/00
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