| 发明名称 |
COMPOSITIONS FOR TREATING ISCHEMIA-RELATED NEURONAL DAMAGE |
| 摘要 |
A pharmaceutical composition effective in reducing neuronal damage related t o an ischemic condition in a mammalian species. The composition includes a neuronal calcium-channel antagonist compound effective to block norepinephrine release in mammalian CNS neuronal cells, and characterized by specific high affinity binding to an omega-conotoxin MVIIA binding pro- tein. Also disclosed are novel omega-conotoxin peptides.
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| 申请公布号 |
CA2045473(C) |
申请公布日期 |
2002.09.17 |
| 申请号 |
CA19902045473 |
申请日期 |
1990.11.21 |
| 申请人 |
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发明人 |
MILJANICH, GEORGE P.;BITNER, ROBERT S.;BOWERSOX, STEPHEN S.;FOX, JAMES A.;VALENTINO, KAREN L.;YAMASHIRO, DONALD H. |
| 分类号 |
A61K38/00;A61P9/10;A61P25/00;C07K7/00;C07K14/435;C07K14/47;C07K14/705;(IPC1-7):C07K14/435;A61K38/17 |
主分类号 |
A61K38/00 |
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