| 发明名称 |
Amidoaromatic ring sulfonamide hydroxamic acid compounds |
| 摘要 |
An amidoaromatic ring sulfonamide hydroxamic acid compound that inter alia inhibits matrix metalloprotease activity is disclosed, as are a treatment process that comprises administering a contemplated amidoaromatic ring sulfonamide hydroxamic acid compound in a MMP enzyme-inhibiting effective amount to a host having a condition associated with pathological matrix metalloprotease activity.
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| 申请公布号 |
US6451791(B1) |
申请公布日期 |
2002.09.17 |
| 申请号 |
US19990230205 |
申请日期 |
1999.06.04 |
| 申请人 |
MONSANTO COMPANY |
发明人 |
HEINTZ ROBERT M.;GETMAN DANIEL P.;MCDONALD JOSEPH J.;DECRESCENZO GARY A.;HOWARD SUSAN C.;ABBAS S. ZAHEER |
| 分类号 |
C07D249/12;A61K31/18;A61K31/197;A61K31/216;A61K31/27;A61K31/36;A61K31/381;A61K31/40;A61K31/423;A61K31/426;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/443;A61K31/4436;A61K31/4439;A61K31/444;A61K31/445;A61K31/4453;A61K31/4465;A61K31/4545;A61K31/535;A61K31/5375;A61K31/5377;A61K31/55;A61P1/04;A61P7/02;A61P7/04;A61P9/00;A61P9/02;A61P9/10;A61P13/12;A61P17/02;A61P19/02;A61P19/08;A61P25/00;A61P25/28;A61P27/02;A61P29/00;A61P35/00;A61P35/04;A61P43/00;C07C311/46;C07C323/67;C07D207/08;C07D209/18;C07D209/48;C07D211/14;C07D211/22;C07D213/30;C07D213/32;C07D213/38;C07D213/42;C07D213/70;C07D213/81;C07D213/82;C07D215/36;C07D233/42;C07D233/64;C07D235/28;C07D239/38;C07D239/93;C07D241/12;C07D257/04;C07D263/46;C07D263/58;C07D265/30;C07D271/10;C07D277/20;C07D277/24;C07D277/26;C07D277/36;C07D277/56;C07D277/78;C07D285/08;C07D285/125;C07D295/12;C07D295/13;C07D295/14;C07D295/18;C07D307/38;C07D307/64;C07D307/68;C07D307/79;C07D309/12;C07D317/56;C07D317/62;C07D333/18;C07D333/34;C07D333/38;C07D333/54;C07D401/04;C07D401/12;C07D405/04;C07D409/04;C07D409/12;C07D413/04;C07D413/12;C07D417/12;C07D471/04;C07D513/04;H04N7/088;(IPC1-7):A61K31/18;A61K31/24;A61K31/34 |
主分类号 |
C07D249/12 |
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