发明名称 |
METHOD FOR ASSAYING NON-SPERMINE/SPERMIDINE ACTIVITY OF SPERMIDINE/SPERMINE N<1> ACETYLTRANSFERASE (SSAT) |
摘要 |
This invention relates to a method for assaying activity of the enzyme spermidine/spermine N1-acetyltransferase (SSAT) using SSAT substrates by detecting acetylated forms of the SSAT substrates. SSAT substrates may include amantadine wherein metabolism of amantadine occurs in part by the action of the inducible enzyme SSAT to produce the acetylated metabolite N-acetylamantadine. |
申请公布号 |
WO02070732(A2) |
申请公布日期 |
2002.09.12 |
申请号 |
WO2002CA00265 |
申请日期 |
2002.03.01 |
申请人 |
UNIVERSITY OF MANITOBA |
发明人 |
SITAR, DANIEL, S.;BRAS, ALVARO, P., M. |
分类号 |
C12Q1/48;G01N33/574 |
主分类号 |
C12Q1/48 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|