The invention features a method for diagnosing a malignant neoplasm in a mammal by contacting a bodily fluid from the mammal with an antibody which binds to an human aspartyl (asparaginyl) beta-hydroxylase (HAAH) polypeptide and methods of treating malignant neoplasms by inhibiting HAAH. Methods of inhibiting tumor growth by contacting a tumor cell with an HAAH antisense nucleic acid are also included.
申请公布号
WO0135102(A3)
申请公布日期
2002.09.12
申请号
WO2000US30738
申请日期
2000.11.08
申请人
RHODE ISLAND HOSPITAL, A LIFESPAN PARTNER;WANDS, JACK, R.;DE LA MONTE, SUZANNE, M.;INCE, NEDIM;CARLSON, ROLF, I.
发明人
WANDS, JACK, R.;DE LA MONTE, SUZANNE, M.;INCE, NEDIM;CARLSON, ROLF, I.
