摘要 |
<p>Treatment of a racemic lactate derivative with an enzyme having an ability to hydrolyze an ester asymmetrically causes specific hydrolysis of the ester moiety of one of the optical isomers constituting the racemic lactate derivative, and use of the resulting hydrolyzate as an intermediate enables the preparation of an optically active propoxyaniline derivative in a decreased number of steps as compared with the prior art. (A)</p> |