摘要 |
<p>The invention relates to the down-regulation of VEGF expression by destabilization of VEGF mRNA with a protein of the TIS11 family. The invention is useful in the treatment of pathologies resulting from VEGF overexpression such as tumor growth, psoriasis, rheumatoid arthritis, hemangiomas, angiofibromas, diabetic retinopathy, neovascular glaucoma, age-related macular degeneration and rejection of corneal graft.</p> |