发明名称 |
NOVEL ABCG4 TRANSPORTER AND USES THEREOF |
摘要 |
The invention provides isolated nucleic acid molecules, designated ABCG4 transporter nucleic acid molecules, which encode novel ABC transporter family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing ABCG4 transporter nucleic acid molecules, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which an ABCG4 transporter gene has been introduced or disrupted. The invention further provides isolated ABCG4 transporter proteins, fusion proteins, antigenic peptides, anti-ABCG4 transporter antibodies, and screening assays for ABCG4 transporter modulators. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided. |
申请公布号 |
WO02070691(A2) |
申请公布日期 |
2002.09.12 |
申请号 |
WO2002CA00267 |
申请日期 |
2002.03.01 |
申请人 |
ACTIVE PASS PHARMACEUTICALS, INC.;CHEN, HONGYUN;LE BIHAN, STEPHANE |
发明人 |
CHEN, HONGYUN;LE BIHAN, STEPHANE |
分类号 |
A61K38/00;C07K14/705;C12N15/12 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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