发明名称 |
B/b-like fragment targeting for the purposes of photodynamic therapy and medical imaging |
摘要 |
The invention provides compositions and methods for use in delivering a substance of interest to a targeted cell. The substance of interest is associated with a targeting fragment of a toxin molecule or a lectin that specifically binds to a cell surface receptor, such as the B subunit of an A/B type toxin molecule. The substance of interest may be a photosensitizing agent, in which case the cell (e.g. a cancer cell) may be killed by exposure to light after delivery of the agent. Alternatively, the substance of interest may be a visualizing agent that enhances visualization of the targeted cell. |
申请公布号 |
AU2001297644(A1) |
申请公布日期 |
2002.09.12 |
申请号 |
AU20010297644 |
申请日期 |
2001.10.26 |
申请人 |
VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.;CARILION BIOMEDICAL INSTITUTE |
发明人 |
SAM ENGLISH;BRIAN STORRIE;MARIA TARRAGO-TRANI |
分类号 |
A61K41/00;A61K47/48;A61K49/00;A61K49/04;A61K49/08;(IPC1-7):A01N37/18;C07K16/00;C12P21/08 |
主分类号 |
A61K41/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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