A PROCESS FOR THE SEPARATION OF BIOCOMPONENTS ON A SUBSTRATE SURFACE

摘要

The invention relates to a process for the separation of biocomponents, such as tissue, cells, body fluids, proteins, nucleic acids etc. The process comprises the steps of: i. providing a material comprising a substrate that has a surface separation layer on at least a part of its surface; ii. providing a liquid comprising the biocomponents; and iii. contacting the liquid comprising the biocomponents with the surface separation layer. The surface separation layer may preferably comprise a stepwise or continuous gradient in at least one direction along the surface of the substrate. The gradient may include a change in e.g. the thickbess, the cross-linking degree, the density or the molecular weight. The gradient may alternatively include a change in the concentration of one or more components or in the type of components, so that al least one property, such as hydrophilicity or pH value, is changing continuously or stepwise. An electrophoresis technique may be applied to the method.