NARC8 PROGRAMMED CELL-DEATH-ASSOCIATED MOLECULES AND USES THEREOF

摘要

The invention provides isolated nucleic acids molecules, designated NARC8 nucleic acid molecules, which encode novel programmed cell death-associated proteins. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing NARC8 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a NARC8 gene has been introduced or disrupted. The invention still further provides isolated NARC8 proteins, fusion proteins, antigenic peptides and anti-NARC8 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.