| 摘要 |
<p>The invention is directed to assays or kits containing and methods of using NS3 derived from hepatitis C virus protease/helicase that has been found to interact with the 3'-terminal sequence of viral positive-and negative-strand RNA. Assays, kits and methods directed to NS3's associated analogs in other viruses are also described herein. Methods of treatment of a subject having HCV infection are also described, by administration of an agent to the subject which inhibits the binding of helicase to HCV RNA.</p> |
