摘要 |
<p>The invention relates to the field of molecular genetics and medicine. In particular the present invention relates to the field of functional genonics. The present invention provides the methods and means for the identification of nucleic acid and the polypeptides encoded by these nucleic acids that have a function related to the E2F pathway, which were isolated in a high-throughput screening assay using the E2F transcription factor activity as a read-out. The identified compounds are suitable drug-targets to treat human diseases.</p> |