发明名称 |
SOMNOGENIC ACTIVITY OF NON-PATHOGENIC LACTIC ACID BACTERIA |
摘要 |
Non-pathogenic lactic acid bacteria have cell walls which are susceptible to digestion by muramidase-type enzymes, which produce fragments referred to as muramylpeptides. The ingestion of muramylpeptides, either directly, or by digestion of non-pathogenic lactic acid bacteria, promote sleep and improves the quality of sleep. In particular, non-rapid eye movement sleep phase enhanced. The muramylpeptide digestion-products of non-pathogenic lactic acid bacteria promote monocyte production of superoxide anion and the cytokines of IL-1 beta and TNF alpha . |
申请公布号 |
WO0145722(A9) |
申请公布日期 |
2002.09.12 |
申请号 |
WO2000EP13020 |
申请日期 |
2000.12.20 |
申请人 |
COMPAGNIE GERVAIS DANONE |
发明人 |
KRUEGER, JAMES, M.;PABST, MICHAEL, J.;CAYUELA, CHANTAL;DEGIVRY, MARIE-CHRISTINE;HARTLEY, DONNA |
分类号 |
A23L1/30;A23C9/123;A23C11/10;A23L1/03;A61K35/74;A61P25/20 |
主分类号 |
A23L1/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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