AMINOKETONE ASYMMETRIC REDUCTASE AND NUCLEIC ACID THEREOF
摘要
A protein which is an aminoketone asymmetric reductase acting on 1-2-methylaminopropiophenone to form d-pseudoephedrine and having the following physicochemical properties; and a nucleic acid encoding this protein: substrate: 1-2-methylaminopropiophenone; optimum pH value: 8.1; optimum temperature: 55 DEG C; coenzyme: NADP; and molecular weight: homotetramer of about 28500 Da.
申请公布号
WO02070714(A1)
申请公布日期
2002.09.12
申请号
WO2002JP01928
申请日期
2002.03.01
申请人
DAIICHI FINE CHEMICAL CO., LTD.;SAKAMOTO, KEIJI;KITA, SHINJI;TSUZAKI, KAZUYA;MORIKAWA, TADANORI;SHIMIZU, SAKAYU;KATAOKA, MICHIHIKO