| 摘要 |
<p>Compounds of the general formula (I) are useful in the treatment and prevention of beta 3-related diseases including diabetes, obesity and hyperlipidemia wherein R<1> is hydrogen, halogen, or hydroxyl; R<2> is lower alkyl or benzyl; R<3> is OR, halogen, trifluoromethyl, lower alkyl, lower acyl, NR<4>R<4'>, nitro, or cyano; R is hydrogen, lower alkyl, benzyl group, or optionally substituted lower acyl; R<4> and R<4'> are each independently hydrogen, lower alkyl, lower acyl, benzyl, or SO2R<5>; R<5> is lower alkyl or benzyl; W is oxygen, a secondary nitrogen atom (NH), or sulfur; and * represents an asymmetric carbon atom. <CHEM></p> |
