FUSION PROTEIN FOR BLOCKING THE HIV NEF PROTEIN

摘要

The invention relates to a novel fusion protein for blocking the HIV Nef protein. The invention also relates to nucleic acid sequences that code this fusion protein or a biologically active portion thereof, to the complementary sequence thereof, and to an expression vector containing a nucleic acid sequence of this type. The invention further relates to a host cell that is transformed with a vector of the aforementioned type and to a method for creating an essentially pure fusion protein for blocking the HIV Nef protein. Lastly, the invention relates to compositions, which comprise the aforementioned fusion proteins or nucleic acid sequences in conjunction with a pharmaceutically acceptable excipient, and to the use thereof in in vitro diagnosis / in vivro therapy of acquired immunodeficiency syndrome (AIDS).