A method of screening a subject for mitochondrial dysfunction comprises detecting the presence or absence of single nucleotide changes in a hypervariable region of the mitochondrial DNA of said subject, the presence of such changes indicating that said subject is afflicted with or at risk of developing mitochondrial dysfunction.
申请公布号
WO02068689(A1)
申请公布日期
2002.09.06
申请号
WO2001US05979
申请日期
2001.02.24
申请人
CHILDRENS HOSPITAL LOS ANGELES;BOLES, RICHARD, G.;ITO, MASAMICHI