发明名称 |
Increased recovery of active proteins |
摘要 |
The invention provides methods of increasing yields of desired conformation of proteins. In particular embodiments, the invention includes contacting preparations of a recombinant protein with a reduction/oxidation coupling reagent for a time sufficient to increase the relative proportion of a desired configurational isomer. |
申请公布号 |
WO02068455(A2) |
申请公布日期 |
2002.09.06 |
申请号 |
WO2002US05645 |
申请日期 |
2002.02.22 |
申请人 |
IMMUNEX CORP |
发明人 |
SASSENFELD HELMUT M;REMMELE RICHARD L;MCCOY REBECCA E |
分类号 |
A61K38/00;A61K38/17;A61P35/00;C07K1/113;C07K1/22;C07K14/525;C07K14/705;C07K14/715;C07K14/735 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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