发明名称 PHARMACEUTICAL COMPOSITION OF F(AB)2 FRAGMENTS OF ANTIBODIES AND METHOD FOR THE PREPARATION THEREOF
摘要 <p>The invention relates to a pharmaceutical composition comprising F(ab)2 fragments of antibodies, which are preferably free of albumin and complete antibodies and substantially pryrogen-free, and an effective amount of a pharmaceutically acceptable carrier. The invention also relates to a method for the preparation of a pharmaceutical composition comprising F(ab)2 fragments of antibodies, using blood serum or plasma of a previously vaccinated mammal as source of antibodies. The blood serum or plasma is digested with an enzyme (pepsin), after which separation and purification are carried out until the pharmaceutical composition of F(ab)2 is free of albumin and complete antibodies and substantially pyrogen-free..</p>
申请公布号 WO2002068475(A2) 申请公布日期 2002.09.06
申请号 MX2002000013 申请日期 2002.02.28
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