发明名称 |
Fiber optic sensor with encoded microspheres |
摘要 |
A microsphere-based analytic chemistry system and method for making the same is disclosed in which microspheres or particles carrying bioactive agents may be combined randomly or in ordered fashion and dispersed on a substrate to form an array while maintaining the ability to identify the location of bioactive agents and particles within the array using an optically interrogatable, optical signature encoding scheme. In a preferred embodiment, a modified fiber optic bundle or array is employed as a substrate to produce a high density array. The disclosed system and method have utility for detecting target analytes and screening large libraries of bioactive agents. In a preferred embodiment the methods include detecting a change in an optical property around a microsphere on an array.
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申请公布号 |
US2002122612(A1) |
申请公布日期 |
2002.09.05 |
申请号 |
US20010840012 |
申请日期 |
2001.04.20 |
申请人 |
TRUSTEES OF TUFTS COLLEGE |
发明人 |
WALT DAVID R.;MICHAEL KARRI LYNN |
分类号 |
G01N33/543;C12Q1/68;C40B40/10;G01N15/14;G01N21/64;G01N21/77;G01N33/532;G01N35/00;(IPC1-7):G02B6/26;G01N21/76 |
主分类号 |
G01N33/543 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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