| 摘要 |
<p>1,250,303. Spiro-oxazolidinone derivatives. LABORATOIRES JACQUES LOGEAIS. 2 March, 1970 [25 March, 1969], No. 9821/70. Heading C2C. Compounds I where R is hydrocarbyl and R<SP>1</SP> is H or hydrocarbyl are prepared by condensing an N- substituted 4-piperidone II with RiCHiCN to give III converting the compound III to an N-oxide IV by reacting III with H 2 0 2 , the reaction being at least completed in an alkaline medium; reducing IV to an amide V and ring closing the amide V to give I. The conversion of III into IV may be effected in two stages, by first reacting III with H 2 0 2 in an acid medium to give VI and completing the reaction in an alkaline medium to give IV.</p> |
