发明名称 |
Calcium binding proteolipid compositions and methods |
摘要 |
The invention relates to the cloning and sequencing of the DNA encoding a membrane associated proteolipid from C. matruchotii that is capable of inducing in vitro calcium binding. A proteolipid was extracted from cultures of C. matruchotii and separated into a lipid component and three apoproteins having molecular weights of approximately 5.0, 5.5 and 7.5 kDa as determined by SDS-PAGE. The invention also includes the polyclonal and monoclonal antibodies directed against the membrane associated proteolipid and immunological assays developed with these antibodies.
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申请公布号 |
US6444446(B1) |
申请公布日期 |
2002.09.03 |
申请号 |
US19990448192 |
申请日期 |
1999.11.23 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
BOYAN BARBARA D.;DIJK SIMON VAN;DEAN DAVID D. |
分类号 |
C12N15/09;A61K31/00;A61K38/00;A61K39/00;A61K39/395;A61K49/00;A61P1/00;A61P1/02;C07K14/34;C07K16/12;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/31;G01N33/53;(IPC1-7):C12N15/09;A61K39/05 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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