发明名称 |
Method of preparing form II crystals of clarithromycin |
摘要 |
Pure Form II crystals of clarithromycin can be prepared by a simple, high-yield process comprising the steps of treating crude clarithromycin or different crystal forms of clarithromycin with formic acid in an organic solvent to obtain crystalline clarithromycin formate and neutralizing the clarithromycin formate with a base in a mixture of water and a water-miscible organic solvent.
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申请公布号 |
US6444796(B1) |
申请公布日期 |
2002.09.03 |
申请号 |
US20000693795 |
申请日期 |
2000.10.20 |
申请人 |
HANMI PHARM CO., LTD. |
发明人 |
SUH KWEE-HYUN;SEONG MI-RA;KIM NAM-DU;LEE GWAN-SUN |
分类号 |
A61P31/04;C07H17/08;(IPC1-7):C07H1/00 |
主分类号 |
A61P31/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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