Non-invasive detection of endothelial dysfunction by blood flow measurement in opposed limbs using tracer injection

摘要

Endothelial dysfunction is a known indicator of cornary artery disease. Endothelial dysfunction is detected by measuring tracer presence in arteries following the release of blood flow into the limb after a period of blockage of blood flow into the limb. The blood flow is measured in a pair of laterally opposed limbs, such as the patient's forearms, and the tracer presence is compared between both limbs. An efficient tracer is a radionuclide and the non-invasive measurement of the radionuclide is carried out by gamma ray detection.