摘要 |
<p>Cpds. of formula (where R1 and R2 are H, alkyl, aralkyl, a cycloaliphatic gp. or aryl; or CHR1R2 is a 3-7C cycloaliphatic ring or a cycloaliphatic ring with an aromatic ring fused to it) have antiphlogistic and CNS depressant-activity and are inters. for medicaments. They may be prepd. by treating the corresp. 1-R1R2CHCO-substd. deriv. with alkali, pref. dil. NaOH soln. at relatively high temp.</p> |