发明名称 |
NUCLEIC ACID COMPLEX AND COMPOSITION FOR INSERTING THE SAME INTO HIGHER EUKARYOTIC CELLS |
摘要 |
The invention relates to a nucleic acid complex comprising one or more nucleic acids, a first substance having nucleic acid affinity and an endosomolytic agent itself having a range of binding to the nucleic acid or being bound to a second substance having nucleic acid affinity and being identical to or different from the first substance and possibly, an internalization factor, and to a composition for inserting these nucleic acid complexes into higher eukaryotic cells. |
申请公布号 |
RO117861(B1) |
申请公布日期 |
2002.08.30 |
申请号 |
RO19940000499 |
申请日期 |
1992.09.28 |
申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH, INGELHEIM AM RHEIN US THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, CHAPEL HILL, NORTH CAROLINA |
发明人 |
CURIEL DAVID;WAGNER ERNST;COTTEN MATT;ZATLOUKAL KURT;PLANK CHRISTIAN;BIRNSTIEL L MAX;OBERHAUSER BERND;SCHMIDT G M WALTER |
分类号 |
C12N15/09;A61K35/76;A61K38/00;A61K38/21;A61K38/36;A61K39/44;A61K47/48;A61K48/00;A61P31/12;A61P35/00;C07K14/005;C07K14/075;C07K14/095;C07K14/11;C07K14/15;C07K14/16;C07K14/56;C07K14/775;C07K14/79;C07K16/00;C07K16/28;C12N5/10;C12N7/04;C12N15/34;C12N15/41;C12N15/44;C12N15/87;(IPC1-7):C12N15/87 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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