发明名称 NUCLEIC ACID COMPLEX AND COMPOSITION FOR INSERTING THE SAME INTO HIGHER EUKARYOTIC CELLS
摘要 The invention relates to a nucleic acid complex comprising one or more nucleic acids, a first substance having nucleic acid affinity and an endosomolytic agent itself having a range of binding to the nucleic acid or being bound to a second substance having nucleic acid affinity and being identical to or different from the first substance and possibly, an internalization factor, and to a composition for inserting these nucleic acid complexes into higher eukaryotic cells.
申请公布号 RO117861(B1) 申请公布日期 2002.08.30
申请号 RO19940000499 申请日期 1992.09.28
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH, INGELHEIM AM RHEIN US THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, CHAPEL HILL, NORTH CAROLINA 发明人 CURIEL DAVID;WAGNER ERNST;COTTEN MATT;ZATLOUKAL KURT;PLANK CHRISTIAN;BIRNSTIEL L MAX;OBERHAUSER BERND;SCHMIDT G M WALTER
分类号 C12N15/09;A61K35/76;A61K38/00;A61K38/21;A61K38/36;A61K39/44;A61K47/48;A61K48/00;A61P31/12;A61P35/00;C07K14/005;C07K14/075;C07K14/095;C07K14/11;C07K14/15;C07K14/16;C07K14/56;C07K14/775;C07K14/79;C07K16/00;C07K16/28;C12N5/10;C12N7/04;C12N15/34;C12N15/41;C12N15/44;C12N15/87;(IPC1-7):C12N15/87 主分类号 C12N15/09
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