发明名称 METHOD FOR PRODUCING NON-HYDRATED FEXOFENADINE HYDROCHLORIDE AND A NOVEL CRYSTALLINE FORM OBTAINED THEREBY
摘要 The invention relates to non-hydrated fexofenadine hydrochloride which can be obtained from a fexofenadine base and hydrogen chloride, according to the reaction conditions, either in the form of a novel polymorph ("form A"), in an amorphous form, or in the form of a mixture of different polymorphs. Said novel polymorph ("form A") can be used as a therapeutic active ingredient and can be processed to form a pharmaceutical containing the same and a pharmaceutically acceptable carrier. Said pharmaceutical is suitable for use as an antihistaminic agent, an antiallergic agent and/or a bronchodilating agent.
申请公布号 WO02066429(A1) 申请公布日期 2002.08.29
申请号 WO2002CH00027 申请日期 2002.01.17
申请人 CILAG AG;KIRSCH, VOLKER 发明人 KIRSCH, VOLKER
分类号 A61K31/445;A61P11/08;A61P37/08;A61P43/00;C07D211/22;(IPC1-7):C07D211/22 主分类号 A61K31/445
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