发明名称 ANTIBODIES THAT BIND BOTH BCMA AND TACI
摘要 Molecules that interfere with the binding of a tumor necrosis factor receptor with its ligand, such as a soluble receptor or an anti-receptor antibody, have proven usefulness in both basic research and as therapeutics. The present invention provides antibodies that bind two tumor necrosis factor receptor family members: the transmembrane activator and calcium modulator and cyclophilin ligand-interactor (TACI) receptor, and the B-cellmaturation (BCMA) receptor.
申请公布号 CA2438682(A1) 申请公布日期 2002.08.29
申请号 CA20022438682 申请日期 2002.02.06
申请人 ZYMOGENETICS, INC. 发明人 KINDSVOGEL, WAYNE
分类号 A61K38/55;A61K31/195;A61K33/22;A61K38/00;A61K38/22;A61K39/395;A61K51/00;A61P1/04;A61P3/10;A61P7/06;A61P9/00;A61P11/00;A61P11/06;A61P13/12;A61P17/00;A61P17/02;A61P19/02;A61P21/04;A61P25/00;A61P29/00;A61P31/00;A61P31/04;A61P31/12;A61P33/02;A61P35/00;A61P35/02;A61P37/02;A61P37/06;A61P43/00;C07K16/18;C07K16/28;(IPC1-7):C07K16/28;C07K16/46 主分类号 A61K38/55
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