发明名称 |
Nitriloxy derivatives of (R) and (S)-carnitine |
摘要 |
Carnitine derivatives of formula (I) are described in racemic and/or optically active form, as well as the process for their preparation and their use as pharmaceutical anti-angina active ingredients for the treatment of ischaemic heart disease. Also described is a process for producing the (R)-carnitine enantiomer from (S)-carnitine (or vice versa), using the derivatives of formula (I).
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申请公布号 |
US2002119965(A1) |
申请公布日期 |
2002.08.29 |
申请号 |
US20020119954 |
申请日期 |
2002.04.11 |
申请人 |
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. |
发明人 |
PICCOLO ORESTE;CASTAGNANI ROBERTO;DE WITT PAOLO |
分类号 |
A61K31/21;A61K31/22;A61P9/10;C07B53/00;C07B55/00;C07C227/16;C07C227/18;C07C227/30;C07C227/32;C07C229/22;(IPC1-7):A61K31/55;A61K31/445;A61K31/40;C07D223/04 |
主分类号 |
A61K31/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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