发明名称 Nitriloxy derivatives of (R) and (S)-carnitine
摘要 Carnitine derivatives of formula (I) are described in racemic and/or optically active form, as well as the process for their preparation and their use as pharmaceutical anti-angina active ingredients for the treatment of ischaemic heart disease. Also described is a process for producing the (R)-carnitine enantiomer from (S)-carnitine (or vice versa), using the derivatives of formula (I).
申请公布号 US2002119965(A1) 申请公布日期 2002.08.29
申请号 US20020119954 申请日期 2002.04.11
申请人 SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. 发明人 PICCOLO ORESTE;CASTAGNANI ROBERTO;DE WITT PAOLO
分类号 A61K31/21;A61K31/22;A61P9/10;C07B53/00;C07B55/00;C07C227/16;C07C227/18;C07C227/30;C07C227/32;C07C229/22;(IPC1-7):A61K31/55;A61K31/445;A61K31/40;C07D223/04 主分类号 A61K31/21
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