METHOD AND DEVICE FOR ULTRASOUND-ASSISTED TRANSMEMBRANE MEDICAMENT APPLICATION IN VITRO

摘要

The invention relates to a method and a device for ultrasound-assisted transmembrane medicament application in vivo. For locally, externally controllable administration of medicaments directly into living cells, cell clusters and tissue, said medicaments are initially introduced into the body by means of a separate injection so that they can selectively aggregate on or in small vesicles or vesiculae which can be caused to discharge said medicaments to the cell membranes by an additional measure involving ultrasound. Pre-formed gas bubbles entering into intimate contact with the desired active substance either externally or internally, are introduced into the target region in a first separate step. A subsequent cavitation process is triggered externally by an ultrasonic transmitter in a second step.