| 摘要 |
Glycosylated or nonglycosylated proteins of the formula FSH beta -(linker<1>)n<1>-LH beta (1-X)-(linker<2>)n<2>- alpha , wherein FSHss is a vertebrate follicle stimulating hormone beta subunit or a variant thereof; LH beta (1-X) refers to a beta subunit of a vertebrate luteinizing hormone containing positions 1-X where X is an integer of 114-121 or a variant thereof; each "linker" is a hydrophilic, flexible amino acid sequence containing 1-100 amino acid residue; each n is a 0 or 1; and alpha is the alpha subunit of a vertebrate glycoprotein hormone or a variant thereof are useful in protocols to enhance fertility in humans and in animals. |
