发明名称 |
Multivalent T cell receptor complexes |
摘要 |
The present invention relates to a synthetic multivalent T cell receptor complex for binding to a MHC-peptide complex, which multivalent T cell receptor complex comprises a plurality of T cell receptors specific for the MHC-peptide complex. It is preferred that the T cell receptors are refolded recombinant soluble T cell receptors. The synthetic multivalent T cell receptor complex can be used for delivering therapeutic agents or for detecting MHC-peptide complexes, and methods for such uses are also provided.
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申请公布号 |
US2002119149(A1) |
申请公布日期 |
2002.08.29 |
申请号 |
US20010912787 |
申请日期 |
2001.07.25 |
申请人 |
JAKOBSEN BENT KARSTEN;BOULTER JONATHAN MICHAEL |
发明人 |
JAKOBSEN BENT KARSTEN;BOULTER JONATHAN MICHAEL |
分类号 |
G01N33/68;A61K9/127;A61K38/00;A61K47/48;C07K;C07K14/725;C07K19/00;C12N;C12N15/09;C12N15/12;C12P21/02;G01N33/569;(IPC1-7):A61K39/395;A61K38/17;C07K14/74 |
主分类号 |
G01N33/68 |
代理机构 |
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