Human parvovirus B19 proteins and virus-like particles, their production and their use in diagnostic assays and vaccines

摘要

The invention relates to the coat proteins VP1 and VP2 of the human parovirus B19 and virus-like particles consisting of VP2 or of VP1 and VP2. The invention further comprises genetic information in the form of recombinant expression vectors which contain the genes coding for said proteins, and organisms which through genetic manipulation using such vectors have acquired the ability to produce such proteins and/or particles. The invention further comprises uses of such proteins and virus-like particles for diagnostics or vaccination.